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Genetic variants in complement-related genes: potential implications for cancer risk and progression

1 Jul 2025

Abstract excerpt

The complement system is a critical component of the immune system, playing a significant role in pathogen defense and immune regulation. In cancer, it has a complex and dual role, either aiding in immune surveillance or contributing to tumor progression and immune evasion, depending on the specific context. While genetic and epigenetic regulation of complement-related genes has been studied in various diseases,...

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PMID: 40684514
DOI: 10.1016/j.imbio.2025.153100

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