Article
Genetic variation in caspase genes and risk of non-Hodgkin lymphoma: a pooled analysis of 3 population-based case-control studies.
Blood - 9 Jul 2009
Lan Qing, Morton Lindsay M, Armstrong Bruce, Hartge Patricia, Menashe Idan, Zheng Tongzhang, Purdue Mark P, Cerhan James R, Zhang Yawei, Grulich Andrew, Cozen Wendy, Yeager Meredith, Holford Theodore R, Vajdic Claire M, Davis Scott, Leaderer Brian, Kricker Anne, Schenk Maryjean, Zahm Shelia H, Chatterjee Nilanjan, Chanock Stephen J, Rothman Nathaniel, Wang Sophia S
Abstract excerpt
Caspases play a critical role in regulation of apoptosis, cell differentiation, inflammation, and innate immunity, and several are mutated or have altered expression in non-Hodgkin lymphoma (NHL). To study the impact of genetic variation in caspases on NHL risk, we analyzed tag single nucleotide polymorphisms (SNPs) in 12 caspase and related genes in 3 population-based case-control studies (1946 cases and 1808...
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