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Article

Germline variation in complement genes and event-free survival in follicular and diffuse large B-cell lymphoma.

American journal of hematology - 1 Sept 2012

Charbonneau Bridget, Maurer Matthew J, Fredericksen Zachary S, Zent Clive S, Link Brian K, Novak Anne J, Ansell Stephen M, Weiner George J, Wang Alice H, Witzig Thomas E, Dogan Ahmet, Slager Susan L, Habermann Thomas M, Cerhan James R

Abstract excerpt

The complement pathway plays a central role in innate immunity, and also functions as a regulator of the overall immune response. We evaluated whether polymorphisms in complement genes are associated with event-free survival (EFS) in follicular lymphoma (FL) and diffuse large B-cell (DLBCL) lymphoma. We genotyped 167 single nucleotide polymorphisms (SNPs) from 30 complement pathway genes in a prospective cohort...

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Topics

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Share to Antibodies, Monoclonal, Murine-Derived
Share to Complement Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complement System Proteins

Share to Lymphoma, Follicular

Share to Lymphoma, Large B-Cell, Diffuse

Share to Principal Component Analysis

Share to Proportional Hazards Models

Share to Rituximab

Source

Open in PubMed Open full text

Identifiers

PMID: 22718493
DOI: 10.1002/ajh.23273
PMCID: PMC3586263

Genes

EFS
CFH
CFHR1
CFHR5
CLU

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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