Article
Polymorphisms in complement system genes and risk of non-Hodgkin lymphoma.
Environmental and molecular mutagenesis - 1 Mar 2012
Bassig Bryan A, Zheng Tongzhang, Zhang Yawei, Berndt Sonja I, Holford Theodore R, Hosgood H Dean, Hu Wei, Leaderer Brian, Yeager Meredith, Menashe Idan, Boyle Peter, Xu Jun, Zou Kaiyong, Zhu Yong, Chanock Stephen, Rothman Nathaniel, Lan Qing
Abstract excerpt
The complement system plays an important role in inflammatory and immune responses, and recent evidence has suggested that it may also play a role in lymphomagenesis. We evaluated the association between genetic variation in complement system genes and risk of non-Hodgkin lymphoma (NHL) in a population-based case-control study conducted among women in Connecticut. Tag SNPs in 30 complement genes were genotyped in...
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