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Article

Antigen presentation in celiac disease.

Current opinion in immunology - 1 Feb 2009

Qiao Shuo-Wang, Sollid Ludvig M, Blumberg Richard S

Abstract excerpt

Celiac disease is caused by an inappropriate immune response to ingested gluten proteins. As a dietary antigen, gluten undergoes extensive but incomplete proteolytic digestion in the intestinal lumen. The resultant peptide fragments of gluten require deamidation, but not necessarily further intracellular processing for presentation. Recent studies reveal why the disease associated HLA-DQ2 molecule is particularly...

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Identifiers

PMID: 19342211
DOI: 10.1016/j.coi.2009.03.004
PMCID: PMC3901576

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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