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Article

The roles of MHC class II genes and post-translational modification in celiac disease.

Immunogenetics - 1 Aug 2017

Sollid Ludvig M

Abstract excerpt

Our increasing understanding of the etiology of celiac disease, previously considered a simple food hypersensitivity disorder caused by an immune response to cereal gluten proteins, challenges established concepts of autoimmunity. HLA is a chief genetic determinant, and certain HLA-DQ allotypes predispose to the disease by presenting posttranslationally modified (deamidated) gluten peptides to CD4+ T cells. The...

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Source

Identifiers

PMID: 28695286
DOI: 10.1007/s00251-017-0985-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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