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Article

The immune recognition of gluten in coeliac disease

18 Apr 2005

Abstract excerpt

Coeliac disease, the most common intestinal disorder of western populations, is an autoimmune enteropathy caused by an abnormal immune response to dietary gluten peptides that occurs in genetically susceptible individuals carrying the HLA-DQ2 or -DQ8 haplotype. Despite the recent progresses in understanding the molecular mechanisms of mucosal lesions, it remains unknown how increased amounts of gluten peptides...

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PMID: 15932501
DOI: 10.1111/j.1365-2249.2005.02783.x

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