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Article

Analysis of the binding of gluten T-cell epitopes to various human leukocyte antigen class II molecules.

Human immunology - 1 Feb 2008

Bergseng Elin, Sidney John, Sette Alessandro, Sollid Ludvig M

Abstract excerpt

Celiac disease is a prevalent disorder of the small intestine that is caused by an inflammatory reaction to dietary gluten in genetically susceptible individuals. More than 90% of patients express the HLA-DQ2 molecule, whereas DQ8 is carried by most of the remaining patients. DQ2- and DQ8-mediated presentation of gluten peptides to CD4+ T cells is a key event in the pathogenesis of the disease. The association of...

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Source

Identifiers

PMID: 18361933
DOI: 10.1016/j.humimm.2008.01.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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