Article
Relationship between mutagenicity and DNA adduct formation in mammalian cells for fjord- and bay-region diol-epoxides of polycyclic aromatic hydrocarbons.
Chemico-biological interactions - 1 Jan 1991
Phillips D H, Hewer A, Seidel A, Steinbrecher T, Schrode R, Oesch F, Glatt H
Abstract excerpt
Chinese hamster V79 cells were treated with the anti- and syn-diastereomers of the bay- or fjord-region diol-epoxides of four polycyclic aromatic hydrocarbons, namely benzo[a]pyrene (BP), benzo[c]chrysene (BcC), benzo[g]chrysene (BgC) and benzo[c]phenanthrene (BcPh). The frequency of induction of...
Topics
- Animals
- Benzo(a)pyrene
- Cell Survival
- Cells, Cultured
- Cricetinae
- Cricetulus
- DNA
- Isomerism
- Mutagens
- Mutation
- Polycyclic Compounds
