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Article

Regulation of Cdh1-APC function in axon growth by Cdh1 phosphorylation.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Apr 2009

Huynh Mai Anh, Stegmüller Judith, Litterman Nadia, Bonni Azad

Abstract excerpt

The ubiquitin ligase Cdh1-anaphase promoting complex (Cdh1-APC) plays a key role in the control of axonal morphogenesis in the mammalian brain, but the mechanisms that regulate neuronal Cdh1-APC function remain incompletely understood. Here, we have characterized the effect of phosphorylation of Cdh1 at cyclin-dependent kinase (Cdk) sites on Cdh1-APC function in neurons. We replaced nine conserved sites of...

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Identifiers

PMID: 19339626
DOI: 10.1523/JNEUROSCI.5329-08.2009
PMCID: PMC2839872

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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