Article
Drosophila-Cdh1 (Rap/Fzr) a regulatory subunit of APC/C is required for synaptic morphology, synaptic transmission and locomotion.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Nov 2013
Wise Alexandria, Schatoff Emma, Flores Julian, Hua Shao-Ying, Ueda Atsushi, Wu Chun-Fang, Venkatesh Tadmiri
Abstract excerpt
The assembly of functional synapses requires the orchestration of the synthesis and degradation of a multitude of proteins. Protein degradation and modification by the conserved ubiquitination pathway has emerged as a key cellular regulatory mechanism during nervous system development and functio...
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