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Article

O-GlcNAcylation Antagonizes Phosphorylation of CDH1 (CDC20 Homologue 1).

The Journal of biological chemistry - 3 Jun 2016

Tian Jie, Geng Qizhi, Ding Yuehe, Liao Ji, Dong Meng-Qiu, Xu Xingzhi, Li Jing

Abstract excerpt

The anaphase promoting complex/cyclosome (APC/C) orchestrates various aspects of the eukaryotic cell cycle. One of its co-activators, Cdh1, is subject to myriad post-translational modifications, such as phosphorylation and ubiquitination. Herein we identify the O-linked N-acetylglucosamine (O-GlcNAc) modification that occurs on Cdh1. Cdh1 is O-GlcNAcylated in cultured cells and mouse brain extracts. Mass...

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Share to Acetylglucosamine
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27080259
DOI: 10.1074/jbc.M116.717850
PMCID: PMC4933264

Genes

APC
CDC20
CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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