Article
WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication.
Environmental and molecular mutagenesis - 1 Jul 2009
Walker Dale M, Kajon Adriana E, Torres Salina M, Carter Meghan M, McCash Consuelo L, Swenberg James A, Upton Patricia B, Hardy Andrew W, Olivero Ofelia A, Shearer Gene M, Poirier Miriam C, Walker Vernon E
Abstract excerpt
The success of nucleoside reverse transcriptase inhibitors (NRTIs) in treating HIV-1 infection and reducing mother-to-child transmission of the virus during pregnancy is accompanied by evidence that NRTIs cause long-term health risks for cancer and mitochondrial disease. Thus, agents that mitigat...
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