Article
Whole-genome association studies of sporadic amyotrophic lateral sclerosis: are retroelements involved?
Trends in molecular medicine - 1 Apr 2009
Mougeot Jean-Luc, Richardson-Milazi Stephanie, Brooks Benjamin Rix
Abstract excerpt
Whole-genome association studies (WGASs) have identified single-nucleotide polymorphisms (SNPs) associated with sporadic amyotrophic lateral sclerosis (sALS). However, WGASs have so far produced results that are not consistent with those obtained from monogenic association studies focused on genes found to be relevant to ALS in functional biological studies. We propose that such inconsistencies might be at least...
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