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Article

Genetic and epigenetic studies of amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis & frontotemporal degeneration - 1 May 2013

Al-Chalabi Ammar, Kwak Shin, Mehler Mark, Rouleau Guy, Siddique Teepu, Strong Michael, Leigh Peter Nigel

Abstract excerpt

The identification of genetic and epigenetic factors that are associated with an increased risk of developing amyotrophic lateral sclerosis (ALS), or that modify the age of onset or rate of progression, requires a multimodal research strategy, facilitated through international collaboration. The discovery of several ALS genes strongly linked to RNA biology, the proteasome pathway, and axonal transport suggest...

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Identifiers

PMID: 23678879
DOI: 10.3109/21678421.2013.778571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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