Article
Genetic studies of amyotrophic lateral sclerosis: controversies and perspectives.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases - 1 Feb 2009
Beleza-Meireles Ana, Al-Chalabi Ammar
Abstract excerpt
The genetic causes of amyotrophic lateral sclerosis (ALS) are slowly being dissected out with the help of recent advances in genetic technology. Linkage studies and association studies examining candidate genes, candidate pathways, and genome-wide association have been used, based on direct sequencing and correlations between genetic variations. Copy number and microsatellite variants have also been examined,...
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