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Article

Linking somatic genetic alterations in cancer to therapeutics.

Current opinion in cell biology - 1 Apr 2009

Stuart Darrin, Sellers William R

Abstract excerpt

Somatic genetic alterations provide the foundation for the evolution of human tumors as well as significant opportunity for therapeutic intervention. This review will cover the growing list of examples where somatic genetic alterations have successfully been coupled with a targeted agent resulting in positive clinical outcome. For example, recent data from randomized clinical trials support the earlier...

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Identifiers

PMID: 19328671
DOI: 10.1016/j.ceb.2009.02.001

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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