Article
Using genetics and genomics strategies to personalize therapy for cancer: focus on melanoma.
Biochemical pharmacology - 1 Sept 2010
Nathanson Katherine L
Abstract excerpt
Individualizing therapeutic selection for patients is a major goal in cancer treatment today. This goal is best facilitated by understanding both an individual's inherited genetic variation and the somatic genetic changes arising during cancer development. Clinical decision making based on inherited genetic variation is done for those patients with cancer susceptibility syndromes and more generally to personalize...
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