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Article

Single Nef proteins from HIV type 1 subtypes C and F fail to upregulate invariant chain cell surface expression but are active for other functions.

AIDS research and human retroviruses - 1 Mar 2009

Turk Gabriela, Gundlach Swantje, Carobene Mauricio, Schindler Michael, Salomon Horacio, Benaroch Philippe

Abstract excerpt

HIV-1 Nef protein plays a major role in viral immunopathogenesis, modulating surface expression of several immune receptors, altering signal transduction pathways, and enhancing viral infectivity, among other activities. Nef also exhibits great intersubtype diversity, but most studies have been focused only on Nef proteins from subtype B. Thus, little is known about the functional capacities of nonsubtype B Nef...

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Share to Antigens, Differentiation, B-Lymphocyte
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class II

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Share to nef Gene Products, Human Immunodeficiency Virus

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Source

Identifiers

PMID: 19327048
DOI: 10.1089/aid.2008.0132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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