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Article

Mitochondrial whims: metabolic rate, longevity and the rate of molecular evolution.

Biology letters - 23 Jun 2009

Galtier Nicolas, Jobson Richard W, Nabholz Benoît, Glémin Sylvain, Blier Pierre U

Abstract excerpt

The evolutionary rate of mitochondrial DNA (mtDNA) is highly variable across lineages in animals, and particularly in mammals. This variation has been interpreted as reflecting variations in metabolic rate: mitochondrial respiratory activity would tend to generate mutagenic agents, thus increasing the mutation rate. Here we review recent evidence suggesting that a direct, mechanical effect of species metabolic...

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Identifiers

PMID: 19324654
DOI: 10.1098/rsbl.2008.0662
PMCID: PMC2679905

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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