Article
Disentangling the intertwined roles of mutation, selection and drift in the mitochondrial genome.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 20 Jan 2020
Schaack Sarah, Ho Eddie K H, Macrae Fenner
Abstract excerpt
Understanding and quantifying the rates of change in the mitochondrial genome is a major component of many areas of biological inquiry, from phylogenetics to human health. A critical parameter in understanding rates of change is estimating the mitochondrial mutation rate (mtDNA MR). Although the first direct estimates of mtDNA MRs were reported almost 20 years ago, the number of estimates has not grown markedly...
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