Article
High-throughput sequencing reveals inbreeding depression in a natural population.
Proceedings of the National Academy of Sciences of the United States of America - 11 Mar 2014
Hoffman Joseph I, Simpson Fraser, David Patrice, Rijks Jolianne M, Kuiken Thijs, Thorne Michael A S, Lacy Robert C, Dasmahapatra Kanchon K
Abstract excerpt
Proxy measures of genome-wide heterozygosity based on approximately 10 microsatellites have been used to uncover heterozygosity fitness correlations (HFCs) for a wealth of important fitness traits in natural populations. However, effect sizes are typically very small and the underlying mechanisms remain contentious, as a handful of markers usually provides little power to detect inbreeding. We therefore used...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.