Article
A novel prostate cancer susceptibility locus at 19q13.
Cancer research - 1 Apr 2009
Hsu Fang-Chi, Sun Jielin, Wiklund Fredrik, Isaacs Sarah D, Wiley Kathleen E, Purcell Lina D, Gao Zhengrong, Stattin Pär, Zhu Yi, Kim Seong-Tae, Zhang Zheng, Liu Wennuan, Chang Bao-Li, Walsh Patrick C, Duggan David, Carpten John D, Isaacs William B, Grönberg Henrik, Xu Jianfeng, Zheng S Lilly
Abstract excerpt
A two-stage genome-wide association study (GWAS) of the Cancer Genetic Markers of Susceptibility (CGEMS) initiative identified single nucleotide polymorphisms (SNP) in 150 regions across the genome that may be associated with prostate cancer (PCa) risk. We filtered these results to identify 43 independent SNPs where the frequency of the risk allele was consistently higher in cases than in controls in each of the...
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