Article
Replication of prostate cancer risk loci on 8q24, 11q13, 17q12, 19q33, and Xp11 in African Americans.
The Prostate - 15 Feb 2010
Hooker Stanley, Hernandez Wenndy, Chen Hankui, Robbins Christiane, Torres Jada Benn, Ahaghotu Chiledum, Carpten John, Kittles Rick A
Abstract excerpt
BACKGROUND: Prostate cancer (Pca) is a common malignancy that disproportionately affects African American men (AA). Recently there have been several genome-wide association studies (GWAS) implicating new prostate cancer risk loci along chromosomes 2, 3, 6, 7, 8, 10, 11, 12, 17, 19, and X in populations of European ancestry. Given the higher incidence and mortality for AAs, and differences in allele frequencies...
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