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Article

HLA-B51 and haplotypic diversity of B-Cw associations: implications for matching in unrelated hematopoietic stem cell transplantation.

Tissue antigens - 1 Apr 2009

Bettens F, Nicoloso de Faveri G, Tiercy J-M

Abstract excerpt

In unrelated hematopoietic stem cell transplantation (HSCT), human leukocyte antigen (HLA)-C locus incompatibilities occur frequently and are associated with increased risk of posttransplant complications. Because HLA-B51 is associated with a high rate of Cw disparities, we performed a comprehensive four-digit typing analysis of 140 ABCDRB1 B51 genotypes proven by pedigree analysis and 311 unrelated donors...

Topics

Genetic Variation
Genetics, Population
Genotype
HLA-B Antigens
HLA-B51 Antigen
HLA-C Antigens
Haplotypes
Hematopoietic Stem Cell Transplantation
Histocompatibility Testing
Humans
Microsatellite Repeats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Tissue Donors

Source

Identifiers

PMID: 19317740
DOI: 10.1111/j.1399-0039.2009.01215.x

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