Article
High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation.
Blood - 15 Dec 2007
Lee Stephanie J, Klein John, Haagenson Michael, Baxter-Lowe Lee Ann, Confer Dennis L, Eapen Mary, Fernandez-Vina Marcelo, Flomenberg Neal, Horowitz Mary, Hurley Carolyn K, Noreen Harriet, Oudshoorn Machteld, Petersdorf Effie, Setterholm Michelle, Spellman Stephen, Weisdorf Daniel, Williams Thomas M, Anasetti Claudio
Abstract excerpt
The relative importance of various human leukocyte antigen (HLA) loci and the resolution level at which they are matched has not been fully defined for unrelated donor transplantation. To address this question, National Marrow Donor Program data from 3857 transplantations performed from 1988 to 2003 in the United States were analyzed. Patient-donor pairs were fully typed for HLA-A, -B, -C, -DRB1, -DQB1, -DQA1,...
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