Article
Estimation of high-resolution HLA-A, -B, -C, -DRB1 allele and haplotype frequencies based on 8862 German stem cell donors and implications for strategic donor registry planning.
Human immunology - 1 Nov 2009
Schmidt Alexander H, Baier Daniel, Solloch Ute V, Stahr Andrea, Cereb Nezih, Wassmuth Ralf, Ehninger Gerhard, Rutt Claudia
Abstract excerpt
Human leukocyte antigen (HLA) haplotype frequency distributions in specific populations can be applied to optimize both individual stem cell donor searches and donor registry planning. We present allele and haplotype frequencies derived from a data set of 8862 German stem cell donors who were typed at high resolution for the HLA-A, HLA-B, HLA-C, and HLA-DRB1 genes upon registration. Calculated haplotype...
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