Article
Contribution of HLA-A/B/C/DRB1/DQB1 common haplotypes to donor search outcome in unrelated hematopoietic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Nov 2011
Pédron Béatrice, Guérin-El Khourouj Valérie, Dalle Jean-Hugues, Ouachée-Chardin Marie, Yakouben Karima, Corroyez France, Auvrignon Anne, Petit Arnaud, Landman-Parker Judith, Leverger Guy, Baruchel André, Sterkers Ghislaine
Abstract excerpt
In unrelated hematopoietic stem cell transplantation (HSCT), the prediction of donor search outcome at the time of search initiation is of great value for the physicians to delineate the strategy of patient care. The probability of finding an unrelated donor is high for patients who carry at least 1 of the 10 most common HLA haplotypes in Caucasians. As only 10% to 20% patients respond to this criterion, here we...
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