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Article

Association study of APC polymorphisms with colorectal cancer in Han Chinese.

Clinical biochemistry - 1 Dec 2012

Huang Xiaoye, Wang Yang, Yu Tao, Liu Baocheng, Li Xin, Li Weidong, Chen Shiqing, Zhao Qingzhu, Li Xingwang, Yang Fengping, Wang Quan, Wang Jinfen, Xiao Yanzeng, Xu Yifeng, Feng Guoyin, Peng Zhihai, He Lin, He Guang

Abstract excerpt

OBJECTIVES: Colorectal cancer (CRC) is a common malignancy with worldwide prevalence. Familial adenomatous polyposis (FAP), a predisposition syndrome of CRC, is caused by germ line mutations in the APC gene. Mutations in APC are thought to be an early event in colorectal tumorigenesis. We hypothesized that common variants in APC might be associated with CRC. DESIGN AND METHODS: A case-control study genotyping ten...

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Identifiers

PMID: 22796397
DOI: 10.1016/j.clinbiochem.2012.07.001

Genes

APC
FAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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