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Article

Lack of association between common polymorphisms of epidermal growth factor receptors and nonsyndromic cleft lip with or without cleft palate.

International journal of pediatric otorhinolaryngology - 1 Jul 2009

Martinelli M, Scapoli L, Pezzetti F, Spinelli G, Lunardi S, Carinci F

Abstract excerpt

OBJECTIVES: Nonsyndromic cleft lip with or without cleft palate (CL/P) is a frequent craniofacial malformation with a complex aetiology. Since the first report of an association between DNA sequence variants at the transforming growth factor alpha gene (TGFA) and nonsyndromic oral clefts, several studies have been carried out, which have produced conflicting results. Overall, TGFA is considered as a genetic...

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Source

Identifiers

PMID: 19307027
DOI: 10.1016/j.ijporl.2009.02.013

Genes

TGFA
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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