Article
TGFα/HinfI Polymorphisms Contribute to Nonsyndromic Cleft Lip and Palate in Turkish Patients.
Genetic testing and molecular biomarkers - 1 Sept 2018
Derelli Tufekci Ebru, Ozdiler Erhan, Altug Ayse Tuba, Sancak Ozlem, Ozdiler Orhan, Tastan Hakki
Abstract excerpt
BACKGROUND: Nonsyndromic cleft lip with/without cleft palate (nsCL ± P) is one of the most common birth defects of complex etiology, occurring in ∼1/700 live births worldwide. A series of epidemiological studies were conducted to investigate the association between a transforming growth factor alpha (TGFα) polymorphism and nsCL ± P risk. The aim of this study was to investigate the association between the...
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