Article
Few associations of candidate genes with nonsyndromic orofacial clefts in the population of Lithuania.
Journal of applied genetics - 1 Jan 2007
Morkūniené Ausra, Steponaviciūt Danguole, Utkus Algirdas, Kucinskas Vaidutis
Abstract excerpt
Nonsyndromic orofacial clefting (NS-OFC) is a common complex multifactorial trait with a considerable genetic component and a number of candidate genes suggested by various approaches. Twenty biallelic and microsatellite DNA markers in the strong candidate loci TGFA, TGFB3, GABRB3, RARA, and BCL3 were analysed for allelic association with the NS-OFC phenotype in 112 nuclear families (proband + both parents) from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
