Article
The functional EGF+61 polymorphism and nonsyndromic oral clefts susceptibility in a Brazilian population.
Journal of applied oral science : revista FOB - 1 Jan 2000
Falagan-Lotsch Priscila, Lopes Talíria Silva, Küchler Erika Calvano, Tannure Patrícia Nivoloni, Costa Marcelo de Castro, Amorim Lidia Maria da Fonte de, Granjeiro José Mauro
Abstract excerpt
Nonsyndromic oral clefts are considered a problem of public health in Brazil, presenting a multifactorial etiology that involves genetic and environmental components, such as maternal alcohol consumption. Several candidate genes have been investigated to identify some association with nonsyndromic clefts risk. The epidermal growth factor (EGF) gene is implicated in the normal craniofacial development and its...
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