Article
BMP4 Polymorphism is Associated With Nonsyndromic Oral Cleft in a Brazilian Population.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Nov 2013
Antunes Leonardo Santos, Küchler Erika Calvano, Tannure Patricia Nivoloni, Costa Marcelo Castro, Gouvêa Cresus Vinicius Depes, Olej Beni, Granjeiro Jose Mauro
Abstract excerpt
Objective : To evaluate the association of the polymorphisms in the TGFB3 gene (rs2268626) and the BMP4 gene (rs17563) with nonsyndromic oral clefts. Design : A hospital-based case-control study was conducted with nonsyndromic oral clefts cases and unaffected controls. Cleft type and tooth agenesis data were collected by clinical examination and confirmed through medical records. Risk factors were obtained...
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