Article
Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection.
Journal of virology - 1 Jun 1995
Freed E O, Englund G, Martin M A
Abstract excerpt
The matrix domain of the human immunodeficiency virus type 1 (HIV-1) Gag protein contains a highly basic region near its amino terminus. It has been proposed that this basic domain, in conjunction with the HIV-1 accessory protein Vpr, is responsible for the localization of the HIV-1 preintegration complex to the nucleus in nondividing cells. It has also been postulated that the matrix basic domain assists in the...
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