Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: clinical description and the role of the 5-HTTLPR.

doi:10.3109/15622975.2011.559270

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Article

Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: clinical description and the role of the 5-HTTLPR.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Oct 2011

Strohmaier Jana, Wüst Stefan, Uher Rudolf, Henigsberg Neven, Mors Ole, Hauser Joanna, Souery Daniel, Zobel Astrid, Dernovsek Mojca Z, Streit Fabian, Schmäl Christine, Kozel Dejan, Placentino Anna, Farmer Anne, McGuffin Peter, Aitchison Katherine J, Rietschel Marcella

Abstract excerpt

OBJECTIVES: Sexual dysfunction (SD) is a frequently reported side-effect of antidepressant treatment, particularly of selective serotonin reuptake inhibitors (SSRIs). In the multicentre clinical and pharmacogenetic GENDEP study (Genome-based Therapeutic Drugs for Depression), the effect of the serotonin transporter gene promoter polymorphism 5-HTTLPR on sexual function was investigated during treatment with...

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PMID: 21388237
DOI: 10.3109/15622975.2011.559270
PMCID: PMC3279131

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