Article
lagC-null and gbf-null cells define key steps in the morphogenesis of Dictyostelium mounds.
Developmental biology - 1 Aug 1998
Sukumaran S, Brown J M, Firtel R A, McNally J G
Abstract excerpt
The transition to multicellularity is a key feature of the Dictyostelium life cycle, and two genes, gbf and lagC, are known to play pivotal roles in regulating this developmental switch. lagC-null and gbf-null cells fail to induce cell-type-specific genes ordinarily expressed during multicellular...
Topics
- Adenosine
- Animals
- Cell Movement
- Cyclic AMP
- DNA-Binding Proteins
- Dictyostelium
- G-Box Binding Factors
- Genes, Fungal
- Genes, Protozoan
- Membrane Proteins
- Models, Genetic
- Morphogenesis