Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

lagC-null and gbf-null cells define key steps in the morphogenesis of Dictyostelium mounds.

Developmental biology - 1 Aug 1998

Sukumaran S, Brown J M, Firtel R A, McNally J G

Abstract excerpt

The transition to multicellularity is a key feature of the Dictyostelium life cycle, and two genes, gbf and lagC, are known to play pivotal roles in regulating this developmental switch. lagC-null and gbf-null cells fail to induce cell-type-specific genes ordinarily expressed during multicellular development. The null mutants also share a similar morphological phenotype: mutant cells repeatedly aggregate to form...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Binding Proteins
Share to Genes, Fungal
Share to Membrane Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Morphogenesis

Share to Mutation

Share to Signal Transduction

Share to Transcription Factors

Source

Identifiers

PMID: 9698452
DOI: 10.1006/dbio.1998.8934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

lagC-null and gbf-null cells define key steps in the morphogenesis of Dictyostelium mounds.PMID 9698452Read ↗

Patterns in Dictyostelium discoideum: the role of myosin II in the transition from the unicellular to the multicellular phase.Semantic proximity Read ↗

Null mutations of the Dictyostelium cyclic nucleotide phosphodiesterase gene block chemotactic cell movement in developing aggregates.Semantic proximity Read ↗

Myosin IB null mutants of Dictyostelium exhibit abnormalities in motility.Semantic proximity Read ↗

Three-dimensional localization of wild-type and myosin II mutant cells during morphogenesis of Dictyostelium.Semantic proximity Read ↗

Regulation of Dictyostelium morphogenesis by RapGAP3.Semantic proximity Read ↗

Shared, unique and redundant functions of three members of the class I myosins (MyoA, MyoB and MyoF) in motility and chemotaxis in Dictyostelium.Semantic proximity Read ↗

RasC plays a role in transduction of temporal gradient information in the cyclic-AMP wave of Dictyostelium discoideum.Semantic proximity Read ↗

Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions.Semantic proximity Read ↗

Assessment of development and chemotaxis in Dictyostelium discoideum mutants.Semantic proximity Read ↗

Chemotaxis to cAMP and slug migration in Dictyostelium both depend on migA, a BTB protein.Semantic proximity Read ↗

Early Developmental Program Shapes Colony Morphology in Bacteria.Semantic proximity Read ↗

Cell motility and SCAR localisation in axenically growing Dictyostelium cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.