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Article

Altered NMDA glutamate receptor antagonist response in individuals with a family vulnerability to alcoholism.

The American journal of psychiatry - 1 Oct 2004

Petrakis Ismene L, Limoncelli Diana, Gueorguieva Ralitza, Jatlow Peter, Boutros Nashaat N, Trevisan Louis, Gelernter Joel, Krystal John H

Abstract excerpt

OBJECTIVE: A family history of alcoholism is a risk factor for the development of ethanol dependence. Ethanol is an antagonist of the N-methyl-d-aspartate (NMDA) glutamate receptor, and alterations in NMDA receptor function are thought to be involved in ethanol abuse and dependence. The purpose o...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15465973
DOI: 10.1176/ajp.161.10.1776

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15465973-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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