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Article

[The NMDA receptor system: genetic risk factor for alcoholism].

Der Nervenarzt - 1 Nov 2005

Schumann G, Saam C, Heinz A, Mann K, Treutlein J

Abstract excerpt

Alcohol dependence is one of the most common addictive diseases and known to be in part genetically transmitted, based on an oligogenic background in which each gene involved contributes only little to the resulting phenotype. Besides influencing other signal transduction mechanisms, alcohol specifically inhibits the NMDA signaling cascade, which mediates the excitatory effects of glutamate in the brain. Target...

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Identifiers

PMID: 15887048
DOI: 10.1007/s00115-005-1917-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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