Article
Molecular basis for class V beta-tubulin effects on microtubule assembly and paclitaxel resistance.
The Journal of biological chemistry - 8 May 2009
Bhattacharya Rajat, Cabral Fernando
Abstract excerpt
Vertebrates produce at least seven distinct beta-tubulin isotypes that coassemble into all cellular microtubules. The functional differences among these tubulin isoforms are largely unknown, but recent studies indicate that tubulin composition can affect microtubule properties and cellular microtubule-dependent behavior. One of the isotypes whose incorporation causes the largest change in microtubule assembly is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
