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Article

Roles of beta-tubulin residues Ala428 and Thr429 in microtubule formation in vivo.

The Journal of biological chemistry - 13 Feb 2009

Joe Patrick A, Banerjee Asok, Ludueña Richard F

Abstract excerpt

The C termini of beta-tubulin isotypes are regions of high sequence variability that bind to microtubule-associated proteins and motors and undergo various post-translational modifications such as polyglutamylation and polyglycylation. Crystallographic analyses have been unsuccessful in resolving tubulin C termini. Here, we used a stepwise approach to study the role of this region in microtubule assembly. We...

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Identifiers

PMID: 19074767
DOI: 10.1074/jbc.M807491200
PMCID: PMC3837401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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