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Article

MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis

10 Mar 2009

Abstract excerpt

BACKGROUND: MicroRNAs are small non-coding RNAs that regulate gene expression through mRNA degradation or translational inhibition. MicroRNAs are emerging as key regulators of normal hematopoiesis and hematologic malignancies. Several miRNAs are differentially expressed during hematopoiesis and their specific expression regulates key functional proteins involved in hematopoietic lineage differentiation. This...

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PMID: 19278969
DOI: 10.3324/haematol.2008.002345

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