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Article

Let-7 microRNAs are developmentally regulated in circulating human erythroid cells

25 Nov 2009

Abstract excerpt

BACKGROUND: MicroRNAs are approximately 22nt-long small non-coding RNAs that negatively regulate protein expression through mRNA degradation or translational repression in eukaryotic cells. Based upon their importance in regulating development and terminal differentiation in model systems, erythrocyte microRNA profiles were examined at birth and in adults to determine if changes in their abundance coincide with...

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Share to Erythrocyte Function and Pathophysiology
Share to Hemoglobinopathies and Related Disorders
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PMID: 19939273
DOI: 10.1186/1479-5876-7-98

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