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Article

The therapeutic potential of LRRK2 and alpha-synuclein in Parkinson's disease.

Antioxidants & redox signaling - 1 Sept 2009

Sen Saurabh, West Andrew B

Abstract excerpt

Current treatments for Parkinson's disease fail to modify disease progression, and the underlying pathogenic mechanisms remain elusive. The identification of specific targets responsible for disease will aid in the development of relevant model systems and the discovery of neuroprotective and neurorestorative therapies. Two promising protein candidates, alpha-synuclein and LRRK2, offer unique insight into the...

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Identifiers

PMID: 19271991
DOI: 10.1089/ars.2009.2430
PMCID: PMC2787962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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