Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Haplotype analysis of the engrailed-2 gene in young-onset Parkinson's disease.

Neuro-degenerative diseases - 1 Jan 2009

Rissling Ida, Strauch Konstantin, Höft Christine, Oertel Wolfgang Hermann, Möller Jens Carsten

Abstract excerpt

BACKGROUND/AIMS: Engrailed-2 is a homeobox transcription factor that is expressed in mesencephalic dopaminergic neurons from development to adulthood and probably plays an important role in the survival of these neurons. METHODS: Here, we investigated six single-nucleotide polymorphisms (SNPs) in the promoter region (rs1345514) or transcribed part (rs3735653, rs6460013, rs1861972, rs2361689, and ) of the...

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Genetic Predisposition to Disease
Share to Haplotypes
Share to Homeodomain Proteins
Share to Nerve Tissue Proteins
Share to Parkinson Disease
Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 19270442
DOI: 10.1159/000207796

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Haplotype analysis of the engrailed-2 gene in young-onset Parkinson's disease.PMID 19270442Read ↗

The transcription factor PITX3 is associated with sporadic Parkinson's disease.Semantic proximity Read ↗

Systematic genetic analysis of the PITX3 gene in patients with Parkinson disease.Semantic proximity Read ↗

Autism-associated haplotype affects the regulation of the homeobox gene, ENGRAILED 2.Semantic proximity Read ↗

Intronic single nucleotide polymorphisms of engrailed homeobox 2 modulate the disease vulnerability of autism in a han chinese population.Semantic proximity Read ↗

Association of age at onset in Huntington disease with functional promoter variations in NPY and NPY2R.Semantic proximity Read ↗

Association of transcription factor polymorphisms PITX3 and EN1 with Parkinson's disease.Semantic proximity Read ↗

Transcription factor PITX3 gene in Parkinson's disease.Semantic proximity Read ↗

Sequence analysis of 5' regulatory regions of the Machado-Joseph disease gene (ATXN3).Semantic proximity Read ↗

Evaluation of the LIM homeobox genes LHX6 and LHX8 as candidates for Tourette syndrome.Semantic proximity Read ↗

HOMER1 promoter analysis in Parkinson's disease: association study with psychotic symptoms.Semantic proximity Read ↗

Identification of Multiple QTLs Linked to Neuropathology in the Engrailed-1 Heterozygous Mouse Model of Parkinson's Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.