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Article

The cardiovascular phenotype of a mouse model of acromegaly.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Oct 2009

Izzard Ashley S, Emerson Michael, Prehar Sukhpal, Neyses Ludwig, Trainer Peter, List Edward O, Kopchick John J, Heagerty Anthony M

Abstract excerpt

BACKGROUND: Although, it is accepted that there is an excess of cardiovascular mortality in acromegaly, it is uncertain whether this is due to the direct effects of growth hormone-induced-cardiomyopathy or is a consequence of atherosclerosis secondary to the metabolic syndrome often observed in this condition. Direct comparison of a mouse model of acromegaly to a mouse model of Laron's syndrome allowed us to...

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Source

Identifiers

PMID: 19269870
DOI: 10.1016/j.ghir.2008.12.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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