Article
CYP11B2 -344T/C gene polymorphism and blood pressure in patients with acromegaly.
The Journal of clinical endocrinology and metabolism - 1 Dec 2006
Mulatero Paolo, Veglio Franco, Maffei Pietro, Bondanelli Marta, Bovio Silvia, Daffara Fulvia, Leotta Giannina, Angeli Alberto, Calvo Chiara, Martini Chiara, degli Uberti Ettore C, Terzolo Massimo
Abstract excerpt
CONTEXT: The pathogenesis of increased blood pressure (BP) in acromegaly is unclear, and the role of IGF-I levels and the renin-angiotensin-aldosterone system (RAAS) in this disease remains controversial. OBJECTIVE AND DESIGN: The aim of this study was to investigate the role of gene polymorphisms of the RAAS and involved in sodium handling on BP in acromegaly. SETTING AND PATIENTS: We conducted a multicentric...
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