Article
Magnetic resonance imaging accurately estimates LV mass in a transgenic mouse model of cardiac hypertrophy.
The American journal of physiology - 1 Feb 1998
Franco F, Dubois S K, Peshock R M, Shohet R V
Abstract excerpt
Transgenic mice with a dysfunctional guanylyl cyclase A gene (GCA -/-) are unable to transduce the signals from atrial naturetic peptide and develop hypertension and cardiac hypertrophy. Magnetic resonance imaging (MRI) was performed to assess cardiac hypertrophy in these animals, using wild-type siblings as controls. Anesthetized mice were studied by gated multislice, multiphase cine MRI at 1.5 T. Simpson's rule...
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