Article
Genetic models reveal that brain natriuretic peptide can signal through different tissue-specific receptor-mediated pathways.
Endocrinology - 1 Oct 2000
Chusho H, Ogawa Y, Tamura N, Suda M, Yasoda A, Miyazawa T, Kishimoto I, Komatsu Y, Itoh H, Tanaka K, Saito Y, Garbers D L, Nakao K
Abstract excerpt
Brain natriuretic peptide (BNP), a hormone produced primarily by the cardiac ventricle, is thought to be involved in a variety of homeostatic processes through its cognate receptor, guanylyl cyclase A (GC-A). We previously created transgenic mice overexpressing BNP under the control of the liver-...
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