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Article

Hepatic gene expression in morbidly obese women: implications for disease susceptibility.

Obesity (Silver Spring, Md.) - 1 Aug 2009

Elam Marshall B, Cowan George S, Rooney Robert J, Hiler M Lloyd, Yellaturu Chandrahasa R, Deng Xiong, Howell George E, Park Edwards A, Gerling Ivan C, Patel Divyan, Corton J Christopher, Cagen Lauren M, Wilcox Henry G, Gandhi Malay, Bahr Micheal H, Allan Micheal C, Wodi Linus A, Cook George A, Hughes Thomas A, Raghow Rajendra

Abstract excerpt

The objective of this study was to determine the molecular bases of disordered hepatic function and disease susceptibility in obesity. We compared global gene expression in liver biopsies from morbidly obese (MO) women undergoing gastric bypass (GBP) surgery with that of women undergoing ventral hernia repair who had experienced massive weight loss (MWL) following prior GBP. Metabolic and hormonal profiles were...

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Source

Identifiers

PMID: 19265796
DOI: 10.1038/oby.2009.49

Genes

ABCB11
APOF
DDIT4
ELOVL2
ENO3
IGFBP1
LEPR
LUM
SPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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